
Epitalon
Also called epithalon, epithalamin
- Evidence
- Limited research
- Class
- Pineal tetrapeptide (Ala-Glu-Asp-Gly)
Epitalon belongs to the Pineal tetrapeptide (Ala-Glu-Asp-Gly) class. This library groups it under brain & sleep. Its source category is Not FDA-approved.
At a glance
| Compound class | Pineal tetrapeptide (Ala-Glu-Asp-Gly) |
|---|---|
| Body system | Brain & sleep |
| Use or research focus | Anti-aging, sleep |
| Regulatory status | Not FDA-approved; PCAC voted favorably (Jul 2026) for 503A compounding — final FDA rule pending |
| Source evidence rating | Limited research |
How does Epitalon work?
Claimed telomerase activation / circadian effects.
The source catalog maps this mechanism to Pineal, Whole-body / Metabolic. A biological mechanism describes how a compound interacts with the body; it does not by itself prove a clinical benefit.
What does the evidence tell us?
The source catalog rates the evidence as limited. Laboratory and animal findings cannot establish benefits or safety in people. Small or early studies may raise useful research questions without supporting routine clinical use.
Use the Citations tab to examine the underlying sources. Look for human studies, a relevant comparison group, meaningful outcomes, and adequate follow-up. An ingredient, approved drug, and compounded preparation may have different evidence.
Safety and considerations
For an unapproved use or compound, safety and effectiveness may be uncertain. Products sold for research are not a substitute for prescribed care. Do not infer a human dose, injection protocol, or treatment recommendation from preclinical research.
This library is educational and does not provide dosing or treatment instructions. A listing here does not indicate that Peppy offers the compound.
Common questions
What is Epitalon?
Epitalon belongs to the Pineal tetrapeptide (Ala-Glu-Asp-Gly) class. This library groups it under brain & sleep. Its source category is Not FDA-approved. Its recorded use or research focus is: Anti-aging, sleep.
Is Epitalon FDA-approved?
The catalog records: Not FDA-approved; PCAC voted favorably (Jul 2026) for 503A compounding — final FDA rule pending. Check the current product-specific regulatory information in the source links; a source category does not establish approval for every use or formulation.
How strong is the research?
The source catalog rates the evidence as limited. Laboratory and animal findings cannot establish benefits or safety in people. Small or early studies may raise useful research questions without supporting routine clinical use.
Where can I read the research?
The Citations tab contains 11 reference links from the source dataset. The original research guide provides additional context. These links are a starting point for reading the evidence.
More for brain & sleep
Factual catalog fields and citation links are adapted from Superpower’s Epitalon guide and the public dataset linked in the reference post. Peppy’s explanations are educational; this page does not represent an independent clinical review of every linked study.
Sources & further reading
References associated with Epitalon in the source dataset. Open a source to review its study design, population, limitations, and date.
- 01melatonin rhythmpubmed.ncbi.nlm.nih.gov
- 02telomerasedoi.org
- 03lifespandoi.org
- 04AJMCajmc.com
- 052025 independent replicationpubmed.ncbi.nlm.nih.gov
- 06considered the putative active componentfda.gov
- 07PubMedpubmed.ncbi.nlm.nih.gov
- 08not a federally controlled substancedeadiversion.usdoj.gov
- 09in FDA's Category 1fda.gov
- 10voted 7-4 on July 24, 2026statnews.com
- 11mitochondrial-derived peptidespubmed.ncbi.nlm.nih.gov





