
Dihexa
- Evidence
- Limited research
- Class
- Angiotensin IV-derived peptide
Dihexa belongs to the Angiotensin IV-derived peptide class. This library groups it under brain & sleep. Its source category is Not FDA-approved.
At a glance
| Compound class | Angiotensin IV-derived peptide |
|---|---|
| Body system | Brain & sleep |
| Use or research focus | Cognition (research) |
| Regulatory status | Not FDA-approved (research) |
| Source evidence rating | Limited research |
How does Dihexa work?
HGF/c-Met synaptogenesis.
The source catalog maps this mechanism to Brain / CNS. A biological mechanism describes how a compound interacts with the body; it does not by itself prove a clinical benefit.
What does the evidence tell us?
The source catalog rates the evidence as limited. Laboratory and animal findings cannot establish benefits or safety in people. Small or early studies may raise useful research questions without supporting routine clinical use.
Use the Citations tab to examine the underlying sources. Look for human studies, a relevant comparison group, meaningful outcomes, and adequate follow-up. An ingredient, approved drug, and compounded preparation may have different evidence.
Safety and considerations
For an unapproved use or compound, safety and effectiveness may be uncertain. Products sold for research are not a substitute for prescribed care. Do not infer a human dose, injection protocol, or treatment recommendation from preclinical research.
This library is educational and does not provide dosing or treatment instructions. A listing here does not indicate that Peppy offers the compound.
Common questions
What is Dihexa?
Dihexa belongs to the Angiotensin IV-derived peptide class. This library groups it under brain & sleep. Its source category is Not FDA-approved. Its recorded use or research focus is: Cognition (research).
Is Dihexa FDA-approved?
The catalog records: Not FDA-approved (research). Check the current product-specific regulatory information in the source links; a source category does not establish approval for every use or formulation.
How strong is the research?
The source catalog rates the evidence as limited. Laboratory and animal findings cannot establish benefits or safety in people. Small or early studies may raise useful research questions without supporting routine clinical use.
Where can I read the research?
The Citations tab contains 11 reference links from the source dataset. The original research guide provides additional context. These links are a starting point for reading the evidence.
More for brain & sleep
Factual catalog fields and citation links are adapted from Superpower’s Dihexa guide and the public dataset linked in the reference post. Peppy’s explanations are educational; this page does not represent an independent clinical review of every linked study.
Sources & further reading
References associated with Dihexa in the source dataset. Open a source to review its study design, population, limitations, and date.
- 01maze-based memory testsdoi.org
- 02retracteddoi.org
- 03DOI: 10.5435/JAAOSGlobal-D-25-00236doi.org
- 04removed it from Category 2fda.gov
- 05induced new synapses at picomolar concentrationspmc.ncbi.nlm.nih.gov
- 06formally retracted in April 2025pubmed.ncbi.nlm.nih.gov
- 07also retracted in April 2025pubmed.ncbi.nlm.nih.gov
- 08carries a 2021 expression of concernpubmed.ncbi.nlm.nih.gov
- 09linked to tumor proliferation, invasion, and metastasispubmed.ncbi.nlm.nih.gov
- 10no trial is registered on ClinicalTrials.govclinicaltrials.gov
- 11an independent laboratory in micepubmed.ncbi.nlm.nih.gov





